4th International Conference on Pediatrics and Pediatric Emergency Medicine
Emory University School of Medicine, USA
Title: New methods to identify and cure a common cause of medically intractable epilepsy
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Biography: Larry Olson
Epilepsy is the most common neurological disease in childhood, and fourth most common in adults. Up to 30% of cases cannot be controlled with medication. The most common cause of these medically refractory seizures is a focal cortical dysplasia (FCD), a localized region in the cortex where neuronal formation, migration or lamination is abnormal. These are often seen with high resolution MRI, and are easily resected with a cure rate of up to 85%. However FCDs are also very often “cryptogenic”- extremely small, subtle or inapparent on MRI. This talk will explore why conventional neuroimaging frequently fails, and the development of new methods of image processing which combine MRI and positron emission tomography (PET) in novel ways to expose otherwise invisible FCDs. This process permits successful surgical cures of an otherwise lifelong disease with a significant morbidity and mortality.