Poster 3: Dr Nam Huu Dao
Vietnam National Children’s Hospital, Vietnam
Title: Effective Method of CVVH Treated Acute Crisis Of Organic Academias
Biography
Biography: Poster 3: Dr Nam Huu Dao
Abstract
Background: Organic academia is 1 of 2 kinds of inborn errors of metabolism has often acute crisis in neonate or infection. They will die if we do not diagnose exactly and treat immediately. continuous venovenous hemofiltration (CVVH) is a rescue therapy to remove quickly ammoniac plasma or others toxics of metabolic. Objective: Common about effective of method of CVVH treated acute crisis of organic academias. Materials and methods: describe, prospective 6 severe patients, deep coma, metabolic acidosis, hyperamonaemia, was treated acute crisis of organic academias by CVVH, from 1/2014 to 3/2015. Results: Plasma ammonia levels 822 µmol/l (151-3000 µmol/l) before CVVH, were significantly reduced by 171 ± 54 µmol/l after 12h with CVVH, pH (7,1 ± 0,2) increased 7,32± 0.05 after 48h with CVVH and time medium CVVH is 4.1 ± 4.3 days, Time treatment in ICU is 6,4 ± 5,4 days. Three patients alive, clinical normal, one patient withdrawal treatment due to deep coma., two patients died due to MODS, one patient had nosocomial infection, one patient had Filter clotted. Conclusion: CVVH effectively and quickly eliminates plasma ammonia and correct metabolic acidosis to treat acute crisis of organic academias. Key word: CVVH, organic acidemias, acute crisis, hyperammoniac.